A plant kinesin heavy chain-like protein is a calmodulin-binding protein
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چکیده
منابع مشابه
A plant kinesin heavy chain-like protein is a calmodulin-binding protein.
Calmodulin, a calcium modulated protein, regulates the activity of several proteins that control cellular functions. A cDNA encoding a unique calmodulin-binding protein, PKCBP, was isolated from a potato expression library using protein-protein interaction based screening. The cDNA encoded protein bound to biotinylated calmodulin and 35S-labeled calmodulin in the presence of calcium and failed ...
متن کاملA novel plant calmodulin-binding protein with a kinesin heavy chain motor domain.
Calmodulin, a ubiquitous calcium-binding protein, regulates many diverse cellular functions by modulating the activity of the proteins that interact with it. Here, we report isolation of a cDNA encoding a novel kinesin-like calmodulin-binding protein (KCBP) from Arabidopsis using biotinylated calmodulin as a probe. Calcium-dependent binding of the cDNA-encoded protein to calmodulin is confirmed...
متن کاملInteraction of a kinesin-like calmodulin-binding protein with a protein kinase.
Kinesin-like calmodulin-binding protein (KCBP) is a novel member of the kinesin superfamily that is involved in cell division and trichome morphogenesis. KCBP is unique among all known kinesins in having a myosin tail homology-4 region in the N-terminal tail and a calmodulin-binding region following the motor domain. Calcium, through calmodulin, has been shown to negatively regulate the interac...
متن کاملOrigin and evolution of Kinesin-like calmodulin-binding protein.
Kinesin-like calmodulin-binding protein (KCBP), a member of the Kinesin-14 family, is a C-terminal microtubule motor with three unique domains including a myosin tail homology region 4 (MyTH4), a talin-like domain, and a calmodulin-binding domain (CBD). The MyTH4 and talin-like domains (found in some myosins) are not found in other reported kinesins. A calmodulin-binding kinesin called kinesin-...
متن کاملPlant Kinesin-Like Calmodulin Binding Protein Employs Its Regulatory Domain for Dimerization
Kinesin-like calmodulin binding protein (KCBP), a Kinesin-14 family motor protein, is involved in the structural organization of microtubules during mitosis and trichome morphogenesis in plants. The molecular mechanism of microtubule bundling by KCBP remains unknown. KCBP binding to microtubules is regulated by Ca(2+)-binding proteins that recognize its C-terminal regulatory domain. In this wor...
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ژورنال
عنوان ژورنال: The Plant Journal
سال: 1996
ISSN: 0960-7412,1365-313X
DOI: 10.1046/j.1365-313x.1996.10010009.x